Diets That Need More Research
Though some diets get tons of splashy headlines and online chatter, the scientific support for their effectiveness for weight loss can be limited. Here are two diets that need further research:
GOLO
While most diets preach a message of calorie-cutting, the Golo plan works off the notion that hormone imbalances are at the root of weight loss struggles, leading to hunger, fatigue, binge eating and poor sleep quality. Golo was designed to help balance hormones through its Release supplement and personalized meal plans featuring the kind of foods you’d find in any balanced diet (chicken, fish, fruits and vegetables, whole grains, nuts and seeds), as well as a few less commonly allowed (beef and butter).
- Especially appealing to: People who don’t like to count calories. Golo focuses instead on portion sizes.
- Pros: The Golo plan isn’t overly restrictive, and it offers a 60-day money-back guarantee on your first order.
- Cons: A relative newcomer on the diet landscape, Golo needs randomized clinical trials and observational studies to back up its weight loss claims.
- Potential pitfall: You’re required to pay for the Release supplement to get access to the plan and other materials. Though Golo says its supplement (a proprietary formula made of seven plant-based ingredients and three minerals) is safe for most people, it is not FDA-approved and you should consult your health care provider before taking it. “Many plans that sell an additional item, either a supplement or a device or an extra service, should raise a red flag — unless the item has been tested rigorously in research,” says William Yancy Jr., M.D., medical director of the Duke Lifestyle and Weight Management Center and professor in the Department of Medicine at Duke University School of Medicine. “Dietitians and medical providers can help tease out whether there is evidence (to support the claims) or not.”
KETO
The granddaddy of high-fat, low-carb plans, the keto (short for ketogenic) diet was conceived in the 1920s to treat medical conditions such as epilepsy. There are several variations, but most keto plans allow 70 to 80 percent of your daily calories to come from fat, 10 to 20 percent from protein and 5 to 10 percent from carbs. Keto meal plans are built on meats, nuts, avocados, cheese, fish, poultry and nonstarchy vegetables such as broccoli and leafy greens. Bread and pasta? Don’t even think about it.
- Especially appealing to: Carnivores.
- Pros: Going keto can help you shed pounds if you can stick with it. One small study published in 2020 in Nutrition & Metabolism found that participants, ages 60 to 75, lost an average of nearly 15 pounds after eight weeks.
- Cons: In the beginning, you may suffer what’s known as “keto flu” symptoms (nausea, fatigue, headaches), as your body adjusts. Over the longer term, research suggests, following a keto plan can increase the risk of kidney stones and digestive issues such as constipation, diarrhea and bloating. It could also lead to nutrient deficiencies, high cholesterol, heart disease and cognitive decline. Many dietitians and health care providers do not endorse the KETO diet.
- Potential pitfalls: A low-carb, high-fat plan can be hard to sustain. If you return to carbs, you may gain the weight back. “Any diet that is restrictive in a particular type of food or food group, like carbohydrates, should not be followed unless there is a medical reason,” says Liz Weinandy, dietitian at the Ohio State University Wexner Medical Center and instructor of practice in medical dietetics at OSU. “Even for someone with blood sugar disorders like diabetes, carbohydrates shouldn’t be eliminated but rather limited, and the type of carbohydrates should be a focus.
Intermittent Fasting
Under this plan, it isn’t so much what you eat as when you eat. The three most popular approaches are alternate-day fasting (fast every other day); 5:2 intermittent fasting (eat as you normally would five days a week, then fast or sharply restrict calories for two days); and time-restricted eating, in which you choose a six- to eight-hour daily eating window, which means you are then fasting for 16 to 18 hours a day.
- Especially appealing to: People who want a simplified approach to eating.
- Pros: Although the science is far from conclusive, some research suggests that intermittent fasting may be as effective as calorie-cutting. One review of studies, published in 2022 in Frontiers in Nutrition, suggests that intermittent fasting is more beneficial in reducing body weight, insulin resistance, cholesterol and triglycerides, compared with nonintervention diets.
- Cons: Intermittent fasting may not be a good choice for people with health conditions that require eating at regular intervals (people with diabetes, for instance) or people who are on medications that must be taken multiple times a day and/or with food. “People with serious chronic conditions that require monitoring or medication adjustment should be more careful,” notes William Yancy Jr., M.D., medical director of the Duke Lifestyle and Weight Management Center and professor in the Department of Medicine at Duke University School of Medicine. Studies have also raised concerns about the long-term sustainability and potentially serious health effects of this type of fasting, including cardiovascular disease.
- Potential pitfall: Overeating on nonfasting days or during your eating window. More research is needed about this method’s sustainability and health effects.
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