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5 Things to Know About Pharmacy Networks and Medicare Drug Costs

You could save money on your Rx medications, depending on which pharmacy you visit


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With Medicare Open Enrollment in full swing, you may be exploring and comparing different plan options for 2025. While you’re at it, don’t forget to read up on each plan’s pharmacy network.

Just like health plans have in-network doctors and hospitals, they also have in-network pharmacies, where you’ll save money on your prescription medications. Some plans go a step further and have in-network preferred pharmacies, where consumers stand to pay even less. 

“Many people understand that there are certain pharmacies where their drugs may be less expensive,” says James McSpadden, senior policy advisor at AARP’s Public Policy Institute and the author of a recent AARP report on the topic. “But I'm not sure that people fully grasp the cost differences that may be available” between in- and out-of-network pharmacies, and even between pharmacies within a network."

Here are five things to know about how pharmacy networks work and the steps you can take to make sure you’re getting the best deal on your meds.  

1. You’ll get your plan’s Rx benefits at an in-network pharmacy  

Ever notice how the same medication can cost more at one pharmacy versus another?

If you’re filling your prescription drugs at an out-of-network pharmacy, you’re most likely going to pay more than you would at an in-network pharmacy. That’s because health plans contract with a group, or network, of pharmacies — including in-person pharmacies and mail-order pharmacies — to offer prescription drugs and other services to their members at a lower cost.

So when choosing a prescription drug plan, you’ll want to make sure that your favorite pharmacy (and possibly a few other convenient ones) are included in your plan’s network. Your pharmacy should be able to let you know if it’s in-network for your plan or a plan that you are considering.

2. You may save even more money at a preferred pharmacy  

Within a pharmacy network, your plan may have preferred pharmacies, where you could have even lower out-of-pocket expenses for your medications than an in-network pharmacy that isn’t preferred. These savings vary, but McSpadden’s report notes a recent study which found that people who use a preferred pharmacy could save $2 to $15 per fill on generic drugs.

Preferred pharmacy networks are becoming more common among Medicare health plans. In 2022, 97 percent of Medicare Part D plans had preferred pharmacy networks, up from 13 percent in 2011. Roughly 60 percent of Medicare Advantage Part D plans also utilize preferred pharmacy networks, according to AARP’s report.

3. Drug costs can vary between preferred pharmacies

Here’s where things can get confusing for consumers: The amount you’ll pay for your medications can vary, even between preferred pharmacies, due to differences in negotiations and other variables.

In other words, it may cost you more to fill your medication at one in-network preferred pharmacy than another that’s also preferred. According to AARP’s report, “The variation of annual out-of-pocket cost between preferred pharmacies could be hundreds of dollars, depending on the drug and the plan.”

4. Doing some homework could save you money  

The good news: There are a few ways to find out where you stand to save the most on your prescription medications. Your health plan can tell you which pharmacies in your area are in-network and preferred and what your drugs might cost at these locations. You can also use Medicare’s Plan Finder tool to “get a snapshot” of what your medications may cost at a few different pharmacies in your area, McSpadden says. 

“The best that consumers can do is to do their homework and review their plans,” McSpadden adds. “But all of this can't sit on the back of consumers. We have to do a better job of making sure that plans themselves are being as transparent as possible, and that this information is getting to consumers so that they can make an informed choice, and that it's not overwhelming.”

5. You may want to consider other factors when reviewing your drug plan

In addition to finding a pharmacy that can save you money on your medications, it’s also important to consider whether the pharmacy has convenient hours and is close by or easy to access.

If you’re taking a medication that needs to be compounded by a specialty pharmacy, that’s another thing you’ll need to keep in mind when reviewing your plan, McSpadden says. “And if you live in a rural area where you don't have easy access to a brick-and-mortar pharmacy, then you know you'll need to make sure your plan provides you access to mail-order options,” he adds.

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